Cartoons: approximately 250 (there were often more episodes in one weekly installment though): in total some 75 hours of Smurf cartoons.
Comics: 24 albums, I believe, with one to 5 stories each, and then some books with short gags (one page usually). Many more comics in the magazines and in loose books (e.g. in the 12 square books of 2 or 3 stories each, and the stories in the Pirate collection).
About this Smurfette business: there was some discussion between Peyo and Delporte on the one hand, and the writers at Hanna-Barbera on the other hand, as to what character and looks the Smurfette was supposed to have. The Smurfette is a rather old fashioned kind of woman character, while the US in the early eighties was more for feminism and so on. In the end, Peyo won, as he did with most of those discussions in the first years. But there was no discussion about the inclusion of Smurfette: the question was just what she would be like.
In later years, he loosened the control of the cartoons, which explains the more bizarre (i.e. not very Smurfy) storylines, like all the magical stories with pixies and flying carpets and so on.